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The synthesis of 2-pyrimidinone nucleosides and their incorporation into oligodeoxynucleotides.

The synthesis of 1-(beta-D-2'-deoxyribosyl)-2-pyrimidinone (dK) and its 5-methyl derivative (d5) from 2'-deoxycytidine or 2'-deoxythymidine, respectively, via silver oxide oxidation of 4-hydrazinopyrimidines is described. The necessary hydrazine substituted pyrimidine nucleosides have...

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Bibliografiske detaljer
Main Authors: Gildea, B, McLaughlin, L W
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC317595/
https://ncbi.nlm.nih.gov/pubmed/2704620
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