The synthesis of 2-pyrimidinone nucleosides and their incorporation into oligodeoxynucleotides.
The synthesis of 1-(beta-D-2'-deoxyribosyl)-2-pyrimidinone (dK) and its 5-methyl derivative (d5) from 2'-deoxycytidine or 2'-deoxythymidine, respectively, via silver oxide oxidation of 4-hydrazinopyrimidines is described. The necessary hydrazine substituted pyrimidine nucleosides have been prepared...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1989
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317595/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2704620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.6.2261 |
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