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Calpain Inhibition Attenuates Apoptosis of Retinal Ganglion Cells in Acute Optic Neuritis

PURPOSE. Optic neuritis (ON), inflammation of the optic nerve, is strongly associated with the pathogenesis of multiple sclerosis (MS) and is initiated by the attack of autoreactive T cells against self-myelin antigens, resulting in demyelination, degeneration of retinal ganglion cells (RGCs), and c...

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Bibliografske podrobnosti
Main Authors: Smith, Amena W., Das, Arabinda, Guyton, M. Kelly, Ray, Swapan K., Rohrer, Baerbel, Banik, Naren L.
Format: Artigo
Jezik:Inglês
Izdano: Association for Research in Vision and Ophthalmology, Inc. 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175948/
https://ncbi.nlm.nih.gov/pubmed/21613375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-7027
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