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Inhibition of calpain attenuates encephalitogenicity of MBP-specific T cells

Multiple sclerosis (MS) is a T cell-mediated autoimmune disease of the CNS, possessing both immune and neurodegenerative events that lead to disability. Adoptive transfer (AT) of myelin basic protein (MBP)-specific T cells into naïve female SJL/J mice results in a relapsing-remitting (RR) form of ex...

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Detalhes bibliográficos
Main Authors: Guyton, Mary K., Das, Arabinda, Inoue, Jun, Azuma, Mitsuyoshi, Ray, Swapan K., Brahmachari, Saurav, Banik, Naren L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748265/
https://ncbi.nlm.nih.gov/pubmed/19627443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06287.x
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