Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group

We sequenced 120 candidate genes in 187 high-risk childhood B-precursor acute lymphoblastic leukemias, the largest pediatric cancer genome sequencing effort reported to date. Integrated analysis of 179 validated somatic sequence mutations with genome-wide copy number alterations and gene expression...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Jinghui, Mullighan, Charles G., Harvey, Richard C., Wu, Gang, Chen, Xiang, Edmonson, Michael, Buetow, Kenneth H., Carroll, William L., Chen, I-Ming, Devidas, Meenakshi, Gerhard, Daniela S., Loh, Mignon L., Reaman, Gregory H., Relling, Mary V., Camitta, Bruce M., Bowman, W. Paul, Smith, Malcolm A., Willman, Cheryl L., Downing, James R., Hunger, Stephen P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2011
Konular:
Clinical Trials and Observations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175785/
https://ncbi.nlm.nih.gov/pubmed/21680795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-341412
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