Rapid clearance of transfused murine RBCs is associated with recipient cytokine storm and enhanced alloimmunogenicity

BACKGROUND: 14-day stored RBCs containing an RBC specific transgenic antigen (HOD) induce a recipient pro-inflammatory cytokine storm and are significantly more immunogenic compared to fresh RBCs. Given that recipient mice clear transfused stored RBCs more rapidly than fresh RBCs, we hypothesized th...

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Detalhes bibliográficos
Main Authors: Hendrickson, Jeanne E, Hod, Eldad A., Cadwell, Chantel M., Eisenbarth, Stephanie C., Spiegel, David A., Tormey, Christopher A., Spitalnik, Steven L., Zimring, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175302/
https://ncbi.nlm.nih.gov/pubmed/21569043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2011.03162.x
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