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Failed heart rate recovery at a critical age in 5-HT-deficient mice exposed to episodic anoxia: implications for SIDS

Mice deficient in the transcription factor Pet-1(−/−) have a ∼70% deficiency of brainstem serotonin [5-hydroxytryptamine (5-HT)] neurons and exhibit spontaneous bradycardias in room air at postnatal day (P)5 and P12 and delayed gasping in response to a single episode of anoxia at P4.5 and P9.5 (Cumm...

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Detalhes bibliográficos
Main Authors: Cummings, Kevin J., Commons, Kathryn G., Hewitt, Julie C., Daubenspeck, John A., Li, Aihua, Kinney, Hannah C., Nattie, Eugene E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174796/
https://ncbi.nlm.nih.gov/pubmed/21680874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00336.2011
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