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Caffeine improves the ability of serotonin-deficient (Pet-1(−/−)) mice to survive episodic asphyxia

BACKGROUND: In neonatal rodents, serotonin (5-HT) neurons are critical for successful autoresuscitation. We hypothesized that caffeine, a respiratory stimulant, would hasten the onset of gasping and improve autoresuscitation in 5-HT-deficient, Pet-1(−/−) mice. METHODS: Using a head-out system and el...

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書誌詳細
出版年:Pediatr Res
主要な著者: Cummings, Kevin J., Commons, Kathryn G., Trachtenberg, Felicia L., Li, Aihua, Kinney, Hannah C., Nattie, Eugene E.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399823/
https://ncbi.nlm.nih.gov/pubmed/23095976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2012.142
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