Postnatal loss of brainstem serotonin neurones compromises the ability of neonatal rats to survive episodic severe hypoxia

ABSTRACT: Pet-1(−/−) mice with a prenatal, genetically induced loss of 5-hydroxytryptamine (5-HT, serotonin) neurones are compromised in their ability to withstand episodic environmental anoxia via autoresuscitation. Given the prenatal role of 5-HT neurones in the development of neural networks, her...

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Bibliographic Details
Main Authors: Cummings, Kevin J, Hewitt, Julie C, Li, Aihua, Daubenspeck, John A, Nattie, Eugene E
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2011
Subjects:
Respiratory
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225677/
https://ncbi.nlm.nih.gov/pubmed/21911619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.214445
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