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Oral atorvastatin therapy increases nitric oxide-dependent cutaneous vasodilation in humans by decreasing ascorbate-sensitive oxidants

Elevated low-density lipoproteins (LDL) are associated with cutaneous microvascular dysfunction partially mediated by increased arginase activity, which is decreased following a systemic atorvastatin therapy. We hypothesized that increased ascorbate-sensitive oxidant stress, partially mediated throu...

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Main Authors: Holowatz, Lacy A., Kenney, W. Larry
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174763/
https://ncbi.nlm.nih.gov/pubmed/21715698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00220.2011
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