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In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for persistence in mice

The success of Mycobacterium tuberculosis (Mtb) as a human pathogen relies on its ability to resist eradication by the immune system of healthy individuals. Identification of mechanisms that enable Mtb to persist is key to limiting latent tuberculosis, which affects one third of the world’s populati...

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Autors principals: Gandotra, Sheetal, Schnappinger, Dirk, Monteleone, Mercedes, Hillen, Wolfgang, Ehrt, Sabine
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174471/
https://ncbi.nlm.nih.gov/pubmed/18059281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1683
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