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In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for persistence in mice

The success of Mycobacterium tuberculosis (Mtb) as a human pathogen relies on its ability to resist eradication by the immune system of healthy individuals. Identification of mechanisms that enable Mtb to persist is key to limiting latent tuberculosis, which affects one third of the world’s populati...

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Detalhes bibliográficos
Main Authors: Gandotra, Sheetal, Schnappinger, Dirk, Monteleone, Mercedes, Hillen, Wolfgang, Ehrt, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174471/
https://ncbi.nlm.nih.gov/pubmed/18059281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1683
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