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Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division

The ability of Mycobacterium tuberculosis (Mtb) to persist in its host is central to the pathogenesis of tuberculosis, yet the underlying mechanisms remain incompletely defined. PerM, an integral membrane protein, is required for persistence of Mtb in mice. Here, we show that perM deletion caused a...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wang, Ruojun, Kreutzfeldt, Kaj, Botella, Helene, Vaubourgeix, Julien, Schnappinger, Dirk, Ehrt, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872210/
https://ncbi.nlm.nih.gov/pubmed/31751212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49570
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