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Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division

The ability of Mycobacterium tuberculosis (Mtb) to persist in its host is central to the pathogenesis of tuberculosis, yet the underlying mechanisms remain incompletely defined. PerM, an integral membrane protein, is required for persistence of Mtb in mice. Here, we show that perM deletion caused a...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Wang, Ruojun, Kreutzfeldt, Kaj, Botella, Helene, Vaubourgeix, Julien, Schnappinger, Dirk, Ehrt, Sabine
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872210/
https://ncbi.nlm.nih.gov/pubmed/31751212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49570
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