The design, synthesis and pharmacological characterization of novel β(2)-adrenoceptor antagonists

BACKGROUND AND PURPOSE: Selective and potent antagonists for the β(2)-adrenoceptor are potentially interesting as experimental and clinical tools, and we sought to identify novel ligands with this pharmacology. EXPERIMENTAL APPROACH: A range of pharmacological assays was used to assess potency, affi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hothersall, J Daniel, Black, James, Caddick, Stephen, Vinter, Jeremy G, Tinker, Andrew, Baker, James R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2011
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174413/
https://ncbi.nlm.nih.gov/pubmed/21323900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01269.x
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