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The design, synthesis and pharmacological characterization of novel β(2)-adrenoceptor antagonists
BACKGROUND AND PURPOSE: Selective and potent antagonists for the β(2)-adrenoceptor are potentially interesting as experimental and clinical tools, and we sought to identify novel ligands with this pharmacology. EXPERIMENTAL APPROACH: A range of pharmacological assays was used to assess potency, affi...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Ltd
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174413/ https://ncbi.nlm.nih.gov/pubmed/21323900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01269.x |
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