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On the relationship between block of the cardiac Na(+) channel and drug-induced prolongation of the QRS complex
BACKGROUND AND PURPOSE: Inhibition of the human cardiac Na(+) channel (hNa(v)1.5) can prolong the QRS complex and has been associated with increased mortality in patients with underlying cardiovascular disease. The safety implications of blocking hNa(v)1.5 channels suggest the need to test for this...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174407/ https://ncbi.nlm.nih.gov/pubmed/21480866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01415.x |
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