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Discovery, Synthesis and Biological Evaluation of Novel SMN Protein Modulators
Spinal Muscular Atrophy (SMA) is an autosomal recessive disorder affecting the expression or function of survival motor neuron protein (SMN) due to the homozygous deletion or rare point mutations in the survival motor neuron gene 1 (SMN1). The human genome includes a second nearly identical gene cal...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174349/ https://ncbi.nlm.nih.gov/pubmed/21819082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200497t |
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