Biological roles of the Delta family notch ligand Dll4 in tumor and endothelial cells in ovarian cancer

Emerging evidence suggests that the Notch/Delta-like ligand 4 (DLL4) pathway may offer important new targets for anti-angiogenesis approaches. In this study, we investigated the clinical and biological significance of DLL4 in ovarian cancer. DLL4 was overexpressed in 72% of tumors examined where it...

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Detalhes bibliográficos
Main Authors: Hu, Wei, Lu, Chunhua, Han, Hee Dong, Huang, Jie, Shen, De-yu, Stone, Rebecca L, Nick, Alpa M., Shahzad, Mian M. K., Mora, Edna, Jennings, Nicholas B., Lee, Sun Joo, Roh, Ju-Won, Matsuo, Koji, Nishimura, Masato, Goodman, Blake W., Jaffe, Robert B., Langley, Robert R., Deavers, Michael T, Lopez-Berestein, Gabriel, Coleman, Robert L, Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174342/
https://ncbi.nlm.nih.gov/pubmed/21795478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2719
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