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The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression

Chk1 is a critical effector of DNA damage checkpoints necessary for the maintenance of chromosome integrity during cell cycle progression. Here we report, that Chk1 co-localized with the nucleolar marker, fibrillarin in response to radiation-induced DNA damage in human cells. Interestingly, in vitro...

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Detalhes bibliográficos
Main Authors: Peddibhotla, Sirisha, Wei, Zhubo, Papineni, Rao, Lam, Micheal H, Rosen, Jeffrey M, Zhang, Pumin
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174002/
https://ncbi.nlm.nih.gov/pubmed/21301228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.4.14901
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