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Early-Onset Aging and Defective DNA Damage Response in Cdc14b-Deficient Mice

The Cdc14 dual-specificity phosphatase plays a key role in the mitotic exit of budding yeast cells. Mammals have two homologues, Cdc14a and Cdc14b. Unlike the yeast counterpart, neither Cdc14a nor Cdc14b seems to be essential for mitotic exit. To determine the physiological function of Cdc14b, we ge...

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Detalhes bibliográficos
Main Authors: Wei, Zhubo, Peddibhotla, Sirisha, Lin, Han, Fang, Xiao, Li, Min, Rosen, Jeffrey M., Zhang, Pumin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135283/
https://ncbi.nlm.nih.gov/pubmed/21262768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01330-10
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