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The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis
Defective genome maintenance mechanisms, involving DNA repair and cell-cycle checkpoint pathways, initiate genetic instability in many sporadic and hereditary cancers. The DNA damage effector Checkpoint kinase 1 (Chk1) is a critical component of DNA replication, intra-S phase, and G(2)/M phase check...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663996/ https://ncbi.nlm.nih.gov/pubmed/19289837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806671106 |
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