Recurrent BRAF mutations in Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) has a broad spectrum of clinical behaviors; some cases are self-limited, whereas others involve multiple organs and cause significant mortality. Although Langerhans cells in LCH are clonal, their benign morphology and their lack (to date) of reported recurrent gen...

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Autori principali: Badalian-Very, Gayane, Vergilio, Jo-Anne, Degar, Barbara A., MacConaill, Laura E., Brandner, Barbara, Calicchio, Monica L., Kuo, Frank C., Ligon, Azra H., Stevenson, Kristen E., Kehoe, Sarah M., Garraway, Levi A., Hahn, William C., Meyerson, Matthew, Fleming, Mark D., Rollins, Barrett J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173987/
https://ncbi.nlm.nih.gov/pubmed/20519626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-279083
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