Recurrent BRAF mutations in Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) has a broad spectrum of clinical behaviors; some cases are self-limited, whereas others involve multiple organs and cause significant mortality. Although Langerhans cells in LCH are clonal, their benign morphology and their lack (to date) of reported recurrent gen...

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Bibliographic Details
Main Authors: Badalian-Very, Gayane, Vergilio, Jo-Anne, Degar, Barbara A., MacConaill, Laura E., Brandner, Barbara, Calicchio, Monica L., Kuo, Frank C., Ligon, Azra H., Stevenson, Kristen E., Kehoe, Sarah M., Garraway, Levi A., Hahn, William C., Meyerson, Matthew, Fleming, Mark D., Rollins, Barrett J.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Myeloid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173987/
https://ncbi.nlm.nih.gov/pubmed/20519626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-279083
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