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Critical Role of TCF-1 in Repression of the IL-17 Gene
Overwhelming activation of IL-17, a gene involved in inflammation, leads to exaggerated Th17 responses associated with numerous autoimmune conditions, such as experimental autoimmune encephalomyelitis (EAE). Here we show that TCF-1 is a critical factor to repress IL-17 gene locus by chromatin modifi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173465/ https://ncbi.nlm.nih.gov/pubmed/21935461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024768 |
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