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Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death

BACKGROUND: Alzheimer's disease (AD) is an age related progressive neurodegenerative disorder. One of the reasons for Alzheimer's neuropathology is the generation of large aggregates of Aß42 that are toxic in nature and induce oxidative stress, aberrant signaling and many other cellular al...

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Detalhes bibliográficos
Main Authors: Tare, Meghana, Modi, Rohan M., Nainaparampil, Jaison J., Puli, Oorvashi Roy, Bedi, Shimpi, Fernandez-Funez, Pedro, Kango-Singh, Madhuri, Singh, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173392/
https://ncbi.nlm.nih.gov/pubmed/21949710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024361
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