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Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme

Members of the caspase family of cysteine proteases coordinate the highly disparate processes of apoptosis and inflammation. However, although hundreds of substrates for the apoptosis effector caspases (caspase-3 and caspase-7) have been identified, only two confirmed substrates for the key inflamma...

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Detalhes bibliográficos
Main Authors: Walsh, John G., Logue, Susan E., Lüthi, Alexander U., Martin, Seamus J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173193/
https://ncbi.nlm.nih.gov/pubmed/21757759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225862
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