Metabolic Alterations in Highly Tumorigenic Glioblastoma Cells: PREFERENCE FOR HYPOXIA AND HIGH DEPENDENCY ON GLYCOLYSIS

Recent studies suggest that a small subpopulation of malignant cells with stem-like properties is resistant to chemotherapy and may be responsible for the existence of residual cancer after treatment. We have isolated highly tumorigenic cancer cells with 100-fold increase in tumor initiating capacit...

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Detalhes bibliográficos
Main Authors: Zhou, Yunfei, Zhou, Yan, Shingu, Takashi, Feng, Li, Chen, Zhao, Ogasawara, Marcia, Keating, Michael J., Kondo, Seiji, Huang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173179/
https://ncbi.nlm.nih.gov/pubmed/21795717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.260935
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