SOX9 Protein Induces a Chondrogenic Phenotype of Mesangial Cells and Contributes to Advanced Diabetic Nephropathy

Diabetic nephropathy (DN) is the most important chronic kidney disease. We previously reported that Smad1 transcriptionally regulates the expression of extracellular matrix in DN. Phenotypic change in mesangial cells (MCs) is a key pathologic event in the progression of DN. The aim of this study is...

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Hlavní autoři: Kishi, Seiji, Abe, Hideharu, Akiyama, Haruhiko, Tominaga, Tatsuya, Murakami, Taichi, Mima, Akira, Nagai, Kojiro, Kishi, Fumi, Matsuura, Motokazu, Matsubara, Takeshi, Iehara, Noriyuki, Ueda, Otoya, Fukushima, Naoshi, Jishage, Kou-ichi, Doi, Toshio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173169/
https://ncbi.nlm.nih.gov/pubmed/21795715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244541
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