SOX9 Protein Induces a Chondrogenic Phenotype of Mesangial Cells and Contributes to Advanced Diabetic Nephropathy

Diabetic nephropathy (DN) is the most important chronic kidney disease. We previously reported that Smad1 transcriptionally regulates the expression of extracellular matrix in DN. Phenotypic change in mesangial cells (MCs) is a key pathologic event in the progression of DN. The aim of this study is...

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Autors principals: Kishi, Seiji, Abe, Hideharu, Akiyama, Haruhiko, Tominaga, Tatsuya, Murakami, Taichi, Mima, Akira, Nagai, Kojiro, Kishi, Fumi, Matsuura, Motokazu, Matsubara, Takeshi, Iehara, Noriyuki, Ueda, Otoya, Fukushima, Naoshi, Jishage, Kou-ichi, Doi, Toshio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173169/
https://ncbi.nlm.nih.gov/pubmed/21795715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244541
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