SOX9 Protein Induces a Chondrogenic Phenotype of Mesangial Cells and Contributes to Advanced Diabetic Nephropathy

Diabetic nephropathy (DN) is the most important chronic kidney disease. We previously reported that Smad1 transcriptionally regulates the expression of extracellular matrix in DN. Phenotypic change in mesangial cells (MCs) is a key pathologic event in the progression of DN. The aim of this study is...

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Detalhes bibliográficos
Main Authors: Kishi, Seiji, Abe, Hideharu, Akiyama, Haruhiko, Tominaga, Tatsuya, Murakami, Taichi, Mima, Akira, Nagai, Kojiro, Kishi, Fumi, Matsuura, Motokazu, Matsubara, Takeshi, Iehara, Noriyuki, Ueda, Otoya, Fukushima, Naoshi, Jishage, Kou-ichi, Doi, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173169/
https://ncbi.nlm.nih.gov/pubmed/21795715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244541
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