Reactive Oxygen Species-mediated TRPC6 Protein Activation in Vascular Myocytes, a Mechanism for Vasoconstrictor-regulated Vascular Tone

Both TRPC6 and reactive oxygen species (ROS) play an important role in regulating vascular function. However, their interplay has not been explored. The present study examined whether activation of TRPC6 in vascular smooth muscle cells (VSMCs) by ROS was a physiological mechanism for regulating vasc...

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Main Authors: Ding, Yanfeng, Winters, Ali, Ding, Min, Graham, Sarabeth, Akopova, Irina, Muallem, Shmuel, Wang, Yanxia, Hong, Jeong Hee, Gryczynski, Zygmunt, Yang, Shao-Hua, Birnbaumer, Lutz, Ma, Rong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173128/
https://ncbi.nlm.nih.gov/pubmed/21768109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248344
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