Reactive Oxygen Species-mediated TRPC6 Protein Activation in Vascular Myocytes, a Mechanism for Vasoconstrictor-regulated Vascular Tone

Both TRPC6 and reactive oxygen species (ROS) play an important role in regulating vascular function. However, their interplay has not been explored. The present study examined whether activation of TRPC6 in vascular smooth muscle cells (VSMCs) by ROS was a physiological mechanism for regulating vasc...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ding, Yanfeng, Winters, Ali, Ding, Min, Graham, Sarabeth, Akopova, Irina, Muallem, Shmuel, Wang, Yanxia, Hong, Jeong Hee, Gryczynski, Zygmunt, Yang, Shao-Hua, Birnbaumer, Lutz, Ma, Rong
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173128/
https://ncbi.nlm.nih.gov/pubmed/21768109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248344
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