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BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3 and MAGEA4, is associated with their transcriptional activation in lung cancer

PURPOSE: Aim of this study was to determine if BORIS (Brother of the Regulator Of Imprinted Sites) is a regulator of MAGEA2, 3 and 4 genes in lung cancer. EXPERIMENTAL DESIGN: Changes in expression of MAGEA genes upon BORIS induction/knockdown were studied. Recruitment of BORIS and changes in histon...

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Detalhes bibliográficos
Main Authors: Bhan, Sheetal, Negi, Sandeep S., Shao, Chunbo, Glazer, Chad A., Chuang, Alice, Gaykalova, Daria A., Sun, Wenyue, Sidransky, David, Ha, Patrick K., Califano, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172963/
https://ncbi.nlm.nih.gov/pubmed/21558405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0653
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