Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC.

Cancer/testis antigens (CTAs) were first discovered as immunogenic targets normally expressed in germline cells, but differentially expressed in a variety of human cancers. In this study, we used an integrative epigenetic screening approach to identify coordinately expressed genes in human non-small...

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Detalhes bibliográficos
Main Authors: Chad A Glazer, Ian M Smith, Michael F Ochs, Shahnaz Begum, William Westra, Steven S Chang, Wenyue Sun, Sheetal Bhan, Zubair Khan, Steven Ahrendt, Joseph A Califano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2009-12-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2781168?pdf=render
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