DNA Methylation in the Arginase–Nitric Oxide Synthase Pathway Is Associated with Exhaled Nitric Oxide in Children with Asthma

Rationale: Genetic variation in arginase (ARG) and nitric oxide synthase (NOS) has been associated with exhaled nitric oxide (FeNO) levels in children. Little is known about whether epigenetic variation in these genes modulates FeNO. Objectives: To evaluate whether DNA methylation in ARG and NOS gen...

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Bibliografiske detaljer
Main Authors: Breton, Carrie V., Byun, Hyang-Min, Wang, Xinhui, Salam, Muhammad T., Siegmund, Kim, Gilliland, Frank D.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172885/
https://ncbi.nlm.nih.gov/pubmed/21512169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201012-2029OC
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