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DNA Methylation in the Arginase–Nitric Oxide Synthase Pathway Is Associated with Exhaled Nitric Oxide in Children with Asthma

Rationale: Genetic variation in arginase (ARG) and nitric oxide synthase (NOS) has been associated with exhaled nitric oxide (FeNO) levels in children. Little is known about whether epigenetic variation in these genes modulates FeNO. Objectives: To evaluate whether DNA methylation in ARG and NOS gen...

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Библиографические подробности
Главные авторы: Breton, Carrie V., Byun, Hyang-Min, Wang, Xinhui, Salam, Muhammad T., Siegmund, Kim, Gilliland, Frank D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172885/
https://ncbi.nlm.nih.gov/pubmed/21512169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201012-2029OC
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