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DNA Methylation in the Arginase–Nitric Oxide Synthase Pathway Is Associated with Exhaled Nitric Oxide in Children with Asthma

Rationale: Genetic variation in arginase (ARG) and nitric oxide synthase (NOS) has been associated with exhaled nitric oxide (FeNO) levels in children. Little is known about whether epigenetic variation in these genes modulates FeNO. Objectives: To evaluate whether DNA methylation in ARG and NOS gen...

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Bibliografske podrobnosti
Main Authors: Breton, Carrie V., Byun, Hyang-Min, Wang, Xinhui, Salam, Muhammad T., Siegmund, Kim, Gilliland, Frank D.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172885/
https://ncbi.nlm.nih.gov/pubmed/21512169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201012-2029OC
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