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DNA Methylation in the Arginase–Nitric Oxide Synthase Pathway Is Associated with Exhaled Nitric Oxide in Children with Asthma

Rationale: Genetic variation in arginase (ARG) and nitric oxide synthase (NOS) has been associated with exhaled nitric oxide (FeNO) levels in children. Little is known about whether epigenetic variation in these genes modulates FeNO. Objectives: To evaluate whether DNA methylation in ARG and NOS gen...

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Detalhes bibliográficos
Main Authors: Breton, Carrie V., Byun, Hyang-Min, Wang, Xinhui, Salam, Muhammad T., Siegmund, Kim, Gilliland, Frank D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172885/
https://ncbi.nlm.nih.gov/pubmed/21512169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201012-2029OC
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