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Genetic Variations in Nitric Oxide Synthase and Arginase Influence Exhaled Nitric Oxide Levels in Children

BACKGROUND: Exhaled nitric oxide (FeNO) is a biomarker of airway inflammation. In the nitric oxide (NO) synthesis pathway, nitric oxide synthases (encoded by NOS1, NOS2A and NOS3) and arginases (encoded by ARG1 and ARG2) compete for L-arginine. Although FeNO levels are higher in children with asthma...

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Detalhes bibliográficos
Main Authors: Salam, Muhammad T., Bastain, Theresa M., Rappaport, Edward B., Islam, Talat, Berhane, Kiros, Gauderman, W. James, Gilliland, Frank D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058253/
https://ncbi.nlm.nih.gov/pubmed/21039601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1398-9995.2010.02492.x
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