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Neuronal Production of Transthyretin in Human and Murine Alzheimer's Disease: Is It Protective?
Transthyretin (TTR), a systemic amyloid precursor in the human TTR amyloidoses, interacts with β-amyloid (Aβ) in vitro, inhibits Aβ fibril formation, and suppresses the Alzheimer's disease (AD) phenotype in APP23 mice bearing a human APP gene containing the Swedish autosomal dominant AD mutatio...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172869/ https://ncbi.nlm.nih.gov/pubmed/21880910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2417-11.2011 |
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