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Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Aβ toxicity

Cells that have evolved to produce large quantities of secreted proteins to serve the integrated functions of complex multicellular organisms are equipped to compensate for protein misfolding. Hepatocytes and plasma cells have well developed chaperone and proteasome systems to ensure that secreted p...

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Autors principals: Buxbaum, Joel N., Ye, Zhengyi, Reixach, Natàlia, Friske, Linsey, Levy, Coree, Das, Pritam, Golde, Todd, Masliah, Eliezer, Roberts, Amanda R., Bartfai, Tamas
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268196/
https://ncbi.nlm.nih.gov/pubmed/18272491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712197105
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