Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Aβ toxicity

Cells that have evolved to produce large quantities of secreted proteins to serve the integrated functions of complex multicellular organisms are equipped to compensate for protein misfolding. Hepatocytes and plasma cells have well developed chaperone and proteasome systems to ensure that secreted p...

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Detaylı Bibliyografya
Asıl Yazarlar: Buxbaum, Joel N., Ye, Zhengyi, Reixach, Natàlia, Friske, Linsey, Levy, Coree, Das, Pritam, Golde, Todd, Masliah, Eliezer, Roberts, Amanda R., Bartfai, Tamas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268196/
https://ncbi.nlm.nih.gov/pubmed/18272491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712197105
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