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Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques
In SIV/HIV infection, the gastrointestinal tissue dominates as an important site because of the impact of massive mucosal CD4 depletion and immune activation-induced tissue pathology. Unlike AIDS-susceptible rhesus macaques, natural hosts do not progress to AIDS and resolve immune activation earlier...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
American Society of Hematology
2011
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172794/ https://ncbi.nlm.nih.gov/pubmed/21693759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-339515 |
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