Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques

In SIV/HIV infection, the gastrointestinal tissue dominates as an important site because of the impact of massive mucosal CD4 depletion and immune activation-induced tissue pathology. Unlike AIDS-susceptible rhesus macaques, natural hosts do not progress to AIDS and resolve immune activation earlier...

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Main Authors: Kwa, Suefen, Kannanganat, Sunil, Nigam, Pragati, Siddiqui, Mariam, Shetty, Ravi Dyavar, Armstrong, Wendy, Ansari, Aftab, Bosinger, Steven E., Silvestri, Guido, Amara, Rama Rao
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2011
Assuntos:
Immunobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172794/
https://ncbi.nlm.nih.gov/pubmed/21693759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-339515
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