Expression of Key Regulators of Mitochondrial Biogenesis in Growth Hormone Receptor Knockout (GHRKO) Mice is Enhanced but is Not Further Improved by Other Potential Life-Extending Interventions

Mitochondrial biogenesis is essential for cell viability. Growth hormone receptor knockout (GHRKO), calorie restriction, and surgical visceral fat removal constitute experimental interventions to delay aging and increase life span. We examined the expression of known regulators of mitochondriogenesi...

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Auteurs principaux: Gesing, Adam, Masternak, Michal M., Wang, Feiya, Joseph, Anna-Maria, Leeuwenburgh, Christiaan, Westbrook, Reyhan, Lewinski, Andrzej, Karbownik-Lewinska, Malgorzata, Bartke, Andrzej
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Journal of Gerontology: BIOLOGICAL SCIENCES
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172561/
https://ncbi.nlm.nih.gov/pubmed/21788651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glr080
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