Expression of Key Regulators of Mitochondrial Biogenesis in Growth Hormone Receptor Knockout (GHRKO) Mice is Enhanced but is Not Further Improved by Other Potential Life-Extending Interventions

Mitochondrial biogenesis is essential for cell viability. Growth hormone receptor knockout (GHRKO), calorie restriction, and surgical visceral fat removal constitute experimental interventions to delay aging and increase life span. We examined the expression of known regulators of mitochondriogenesi...

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Detalhes bibliográficos
Main Authors: Gesing, Adam, Masternak, Michal M., Wang, Feiya, Joseph, Anna-Maria, Leeuwenburgh, Christiaan, Westbrook, Reyhan, Lewinski, Andrzej, Karbownik-Lewinska, Malgorzata, Bartke, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Journal of Gerontology: BIOLOGICAL SCIENCES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172561/
https://ncbi.nlm.nih.gov/pubmed/21788651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glr080
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