Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos

Notch, a transmembrane protein found in a wide range of organisms, is a component of a pathway that mediates cell-fate decisions that involve intercellular communication. In this paper, we show that in Drosophila melanogaster, Notch (N) is processed in a ligand-dependent fashion to generate phosphor...

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Bibliographic Details
Main Authors: Kidd, Simon, Lieber, Toby, Young, Michael W.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1998
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC317253/
https://ncbi.nlm.nih.gov/pubmed/9851979
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