Proteolytic cleavage of the THR subunit during anaphase limits Drosophila separase function

Sister-chromatid separation in mitosis requires proteolytic cleavage of a cohesin subunit. Separase, the corresponding protease, is activated at the metaphase-to-anaphase transition. Activation involves proteolysis of an inhibitory subunit, securin, following ubiquitination mediated by the anaphase-...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Herzig, Alf, Lehner, Christian F., Heidmann, Stefan
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 2002
Fag:	Research Paper
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187444/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12231632/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.242202
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!