Transcription factor CREM coordinates the timing of hepatocyte proliferation in the regenerating liver

The liver regenerates upon partial hepatectomy (PH) as terminally differentiated hepatocytes undergo a tremendous proliferative process. CREM gene expression is powerfully induced during liver regeneration. We show that cell proliferation is significantly reduced upon PH in CREM(−/−) mice. There is...

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Pubblicato in:	Genes Dev
Autori principali:	Servillo, Giuseppe, Della Fazia, Maria Agnese, Sassone-Corsi, Paolo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 1998
Soggetti:	Research Communication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9851970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.23.3639
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