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Transcription factor CREM coordinates the timing of hepatocyte proliferation in the regenerating liver

The liver regenerates upon partial hepatectomy (PH) as terminally differentiated hepatocytes undergo a tremendous proliferative process. CREM gene expression is powerfully induced during liver regeneration. We show that cell proliferation is significantly reduced upon PH in CREM(−/−) mice. There is...

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Hlavní autoři: Servillo, Giuseppe, Della Fazia, Maria Agnese, Sassone-Corsi, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC317249/
https://ncbi.nlm.nih.gov/pubmed/9851970
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