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RLIP76, a Glutathione-Conjugate Transporter, Plays a Major Role in the Pathogenesis of Metabolic Syndrome

PURPOSE: Characteristic hypoglycemia, hypotriglyceridemia, hypocholesterolemia, lower body mass, and fat as well as pronounced insulin-sensitivity of RLIP76(−/−) mice suggested to us the possibility that elevation of RLIP76 in response to stress could itself elicit metabolic syndrome (MSy). Indeed,...

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Autors principals: Singhal, Jyotsana, Nagaprashantha, Lokesh, Vatsyayan, Rit, Awasthi, Sanjay, Singhal, Sharad S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172288/
https://ncbi.nlm.nih.gov/pubmed/21931813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024688
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