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Increased Expression of Cdc2 Inhibits Transport Function of RLIP76 and Promotes Apoptosis
RLIP76 is a stress-responsive glutathione-electrophile-conjugates (GS-E) and drugs transporter which is over-expressed in different types of cancers. Cdc2 is a cell-cycle check point control kinase which has been shown to bind to RLIP76 during mitosis, such that endocytosis is inhibited. In present...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2721022/ https://ncbi.nlm.nih.gov/pubmed/19375851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2009.03.033 |
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