Glutathione-Conjugate Transport by RLIP76 is required for Clathrin-Dependent Endocytosis and Chemical Carcinogenesis

Targeted depletion of the RALBP1 encoded 76 kDa splice variant, RLIP76, causes marked and sustained regression of human xenografts of lung, colon, prostate, and kidney cancer without toxicity in nude mouse models. We proposed that the remarkable efficacy and broad-spectrum of RLIP76-targeted therapy...

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Bibliografiske detaljer
Main Authors: Singhal, Sharad S., Wickramarachchi, Dilki, Yadav, Sushma, Singhal, Jyotsana, Leake, Kathryn, Vatsyayan, Rit, Chaudhary, Pankaj, Lelsani, Poorna, Suzuki, Sumihiro, Yang, Shaohua, Awasthi, Yogesh C., Awasthi, Sanjay
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065778/
https://ncbi.nlm.nih.gov/pubmed/21220488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0699
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