Glutathione-Conjugate Transport by RLIP76 is required for Clathrin-Dependent Endocytosis and Chemical Carcinogenesis

Targeted depletion of the RALBP1 encoded 76 kDa splice variant, RLIP76, causes marked and sustained regression of human xenografts of lung, colon, prostate, and kidney cancer without toxicity in nude mouse models. We proposed that the remarkable efficacy and broad-spectrum of RLIP76-targeted therapy...

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Main Authors: Singhal, Sharad S., Wickramarachchi, Dilki, Yadav, Sushma, Singhal, Jyotsana, Leake, Kathryn, Vatsyayan, Rit, Chaudhary, Pankaj, Lelsani, Poorna, Suzuki, Sumihiro, Yang, Shaohua, Awasthi, Yogesh C., Awasthi, Sanjay
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065778/
https://ncbi.nlm.nih.gov/pubmed/21220488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0699
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