Glutathione-Conjugate Transport by RLIP76 is required for Clathrin-Dependent Endocytosis and Chemical Carcinogenesis

Targeted depletion of the RALBP1 encoded 76 kDa splice variant, RLIP76, causes marked and sustained regression of human xenografts of lung, colon, prostate, and kidney cancer without toxicity in nude mouse models. We proposed that the remarkable efficacy and broad-spectrum of RLIP76-targeted therapy...

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Bibliografski detalji
Glavni autori: Singhal, Sharad S., Wickramarachchi, Dilki, Yadav, Sushma, Singhal, Jyotsana, Leake, Kathryn, Vatsyayan, Rit, Chaudhary, Pankaj, Lelsani, Poorna, Suzuki, Sumihiro, Yang, Shaohua, Awasthi, Yogesh C., Awasthi, Sanjay
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065778/
https://ncbi.nlm.nih.gov/pubmed/21220488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0699
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